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KMID : 1134820120410111534
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Journal of the Korean Society of Food Science and Nutrition
2012 Volume.41 No. 11 p.1534 ~ p.1539
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Toxicity Evaluation of Irradiated Tarakjuk for Three Months
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Yin Xing-Fu
Jeon Young-Eun
Kim Tae-Keun
Shim Jae-Hoon
Kang Il-Jun
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Abstract
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This study was conducted to evaluate the possible subacute toxicity of gamma-irradiated Tarakjuk. Tarakjuk was irradiated at a dose of 30 kGy at room temperature. For the animal study, AIN-93G as a control diet and 30 kGy irradiated and non-irradiated Tarakjuk diets were administered to male and female ICR mice (10 mice per group) for 3 months. During the experimental period, the group fed 30 kGy irradiated Tarakjuk did not show any changes in appearance, behavior, mortality, body weight, organ weight, or food consumption compared to control. Further, all biochemical parameters were in normal ranges. In the histopathological examination of liver and kidney tissues of ICR mice, there were no significant differences between the control and 30 kGy irradiated Tarakjuk groups. These results indicate that Tarakjuk irradiated at 30 kGy did not cause any toxic effects under these experimental conditions.
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KEYWORD
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Tarakjuk, gamma irradiation, toxicity, safety
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